This review summarizes the pathophysiological connection of galectin-3 and cancer presently in the literature, as well as the potential clinical value of galectin-3 as a prognostic oncology biomarker. Based on the preliminary data, the galectin-3 assay could become a contributing tool to help clinicians monitor treatment response and tumor progression, but further clinical studies evaluating galectin-3 levels and cancer progression are warranted.
Osteoporosis is estimated to affect more than 10 million Americans, with postmenopausal women at particular risk. Osteoporotic fractures can lead to postural changes, emotional distress, and chronic pain. Currently all medications approved by the US Food and Drug Administration for the treatment of osteoporosis carry slight to modest risks depending on the individual, the duration, the dosage, and the drug being used. Estrogen replacement therapy is not currently indicated for the treatment of osteoporosis, but it is approved for osteoporosis prevention. Interest in bioidentical hormone replacement as an alternative to conventional hormone replacement has increased in the last 12 years, although not always for logical or scientific reasons. The purpose of this review is to bring clinicians up to date on current information on the efficacy and safety of bioidentical hormones for the prevention of postmenopausal osteoporosis.
First published in 1996, this book aims to help students easily understand key concepts in evidence-based medicine and explain the logic and methodology of this approach. This year marks the publication of the fifth edition of the book, which has become a core textbook in medical schools around the world.
Abstracts & Commentary
In a recent study, Epstein Barr virus patients who received intravenous vitamin C demonstrated decreased levels of antigens in the acute state of disease and alleviation of symptoms of the infection.
In a study of 99 recipients of egg donation at the University of Southern California Fertility Center, Los Angeles, vitamin D deficiency was associated with a 50% reduction in pregnancy and live-birth rates in recipients of donor eggs compared to patients who had adequate vitamin D levels.
For this prospective, cohort study, 507 menstrual cycles of 259 eumenorrheic women without a self-reported history of infertility, polycystic ovarian syndrome (PCOS), or other endocrine disorders were tracked over 1 to 2 menstrual cycles. The wide-ranging results support the theory that PCOS can be redefined as polycystic ovary spectrum, with even healthy menstruating women experiencing occasional hormonal dysfunction.
Interviews with Experts
In this interview with naturopathic oncology specialist Adam Kerievsky, ND, LAc, FABNO, we discuss the risk factors for triple-negative breast cancer, the treatment challenges it poses for practitioners, and complementary therapies that may benefit patients battling this cancer.
Michael Friedman, ND, founder and executive director of the Association for the Advancement of Restorative Medicine (AARM), talks to Natural Medicine Journal about the history of this collaborative organization, its publication the Journal of Restorative Medicine, and its conference coming up in October 2014.