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Peer-Reviewed Articles

Bioidentical Hormone Replacement Therapy in Postmenopausal Osteoporosis

By Sarah Bedell Cook, ND
Osteoporosis is estimated to affect more than 10 million Americans, with postmenopausal women at particular risk. Osteoporotic fractures can lead to postural changes, emotional distress, and chronic pain. Currently all medications approved by the US Food and Drug Administration for the treatment of osteoporosis carry slight to modest risks depending on the individual, the duration, the dosage, and the drug being used. Estrogen replacement therapy is not currently indicated for the treatment of osteoporosis, but it is approved for osteoporosis prevention. Interest in bioidentical hormone replacement as an alternative to conventional hormone replacement has increased in the last 12 years, although not always for logical or scientific reasons. The purpose of this review is to bring clinicians up to date on current information on the efficacy and safety of bioidentical hormones for the prevention of postmenopausal osteoporosis.

Effect of Lychee Fruit Extract (Oligonol) on Peripheral Circulation, a Pilot Study

By Kentaro Kitadate, DVM, Kazumasa Aoyagi, MD, PhD, and Kohei Homma, PhD
Poor blood circulation often manifests as small but chronic temperature differences in the peripheral extremities, and the surface of the skin may be an indication of abnormal blood flow and more serious vascular or circulation disorders. This study investigates the effect of Oligonol, a highly bioavailable source of low–molecular weight polyphenols extracted from lychee fruit, on peripheral blood circulation using skin thermography. The results suggest that Oligonol might act as a vasodilator and be an effective treatment for a variety of vasoconstriction symptoms such as cold hands and feet, shoulder discomfort, and diabetes-related vascular problems.

Treatment of Dermal Infections With Topical Coconut Oil

By Lindsey K. Elmore, PharmD, BCPS, Gwen Nance, Samantha Singleton, and Luke Lorenz
Coconut oil, and many other portions of the plant Cocos nucifera L., have been hypothesized to have antimicrobial and antifungal activity. Medium-chain fatty acid constituents of coconut oil including lauric acid, capric acid, and others provide antimicrobial effect by disrupting bacterial, fungal, and viral cell membranes, leading to cell death. This review summarizes in vivo and in vitro studies of topical anti-infective properties of coconut oil and the medium-chain fatty acids contained within, and describes the proposed use of coconut products for dermal infections.

Iodine and Cancer

By Tina Kaczor, ND, FABNO
Iodine is an essential element in human physiology. Its role in thyroid function is well known and heavily weighted in the literature. Its putative role as an anticarcinogenic agent is just beginning to be widely appreciated. The molecular effects of iodine as well as ongoing epidemiological evidence points to its probable role in prevention of cancers through its antioxidant, antiinflammatory, prodifferentiating, and proapoptotic effects. This is particularly evident with stomach and breast cancers but may be relevant for many other cancers that have yet to be substantially studied.

Abstracts & Commentary

Polycystic Ovarian Spectrum

By Jaclyn Chasse, ND
For this prospective, cohort study, 507 menstrual cycles of 259 eumenorrheic women without a self-reported history of infertility, polycystic ovarian syndrome (PCOS), or other endocrine disorders were tracked over 1 to 2 menstrual cycles. The wide-ranging results support the theory that PCOS can be redefined as polycystic ovary spectrum, with even healthy menstruating women experiencing occasional hormonal dysfunction.

Vitamin D Status and In-Vitro Fertilization Outcomes

By Setareh Tais, ND
In a study of 99 recipients of egg donation at the University of Southern California Fertility Center, Los Angeles, vitamin D deficiency was associated with a 50% reduction in pregnancy and live-birth rates in recipients of donor eggs compared to patients who had adequate vitamin D levels.

Interviews with Experts

Managing Triple-negative Breast Cancer: An Interview With Adam Kerievsky, ND, LAc, FABNO

By Tina Kaczor, ND, FABNO
In this interview with naturopathic oncology specialist Adam Kerievsky, ND, LAc, FABNO, we discuss the risk factors for triple-negative breast cancer, the treatment challenges it poses for practitioners, and complementary therapies that may benefit patients battling this cancer.

Expert Guidance on Restoring Patient Health

By Tina Kaczor, ND, FABNO
Michael Friedman, ND, founder and executive director of the Association for the Advancement of Restorative Medicine (AARM), talks to Natural Medicine Journal about the history of this collaborative organization, its publication the Journal of Restorative Medicine, and its conference coming up in October 2014.

Healthcare Perspectives

The Importance of Research Literacy

By Angela Senders, ND, MCR, Andrew Erlandsen, ND, and Heather Zwickey, PhD
The ability to access, interpret, and critically evaluate primary medical literature—is a skill natural medicine practitioners must develop to better educate their patients and promote their profession.

Community News

John Weeks Honored With Lifetime Achievement Living Tribute

By Anne Lanctôt
John Weeks was honored for his 30 years as a leading advocate of integrative medicine with a lifetime achievement living tribute on May 15, 2014, during the International Research Congress on Integrative Medicine and Health (IRCIMH) conference in Miami.

Sponsored Podcasts

Supporting the Pancreatic Cancer Patient: An Interview With Lucas A. Tims, ND, FABNO

By Natural Medicine Journal
In this interview, Lucas A. Tims, ND, FABNO, discusses how integrative medicine practitioners can improve the quality of life for patients diagnosed with pancreatic cancer.





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